A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects
نویسندگان
چکیده
منابع مشابه
Ginsenoside Rg1, a novel glucocorticoid receptor agonist of plant origin, maintains glucocorticoid efficacy with reduced side effects.
Glucocorticoids (GCs) are widely used to treat inflammatory diseases. However, they cause debilitating side effects, which limit the use of these compounds. In the past decade, many researchers have attempted to find so-called dissociated GCs that have separate distinct transactivation and transrepression activities. Anti-inflammation of GCs is a result of glucocorticoid receptor (GR)-mediated ...
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متن کاملGlucocorticoid therapy: minimizing side effects.
OBJECTIVE To describe the main undesirable side effects of glucocorticoid therapy, mechanisms of action and the necessary measures to minimize side effects. SOURCES Author's experience, supplemented with papers published in MEDLINE. SUMMARY OF THE FINDINGS The principles for minimizing undesirable side effects of glucocorticoid therapy include: a) only use glucocorticoids if they are essent...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2003
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2002-0355